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Adobe CC is a discontinued offline website builder used to create fixed, fluid,.. Windows 8.1 (64-bit), Windows 10 (64-bit), or Windows Anniversary Update. Adobe .Role of prostaglandin D2 in the suppression of experimental autoimmune uveoretinitis.
PGD(2) plays an essential role in the induction of T cell-mediated inflammation. The objective of the present study was to determine the effects of dietary PGD(2) on the development of experimental autoimmune uveoretinitis (EAU), and to study the mechanism by which PGD(2) suppressed EAU. The induction of EAU was induced in SJL/J mice fed a balanced diet or PGD(2) supplementation diet. The severity of EAU and infiltrating T cells in the eyes were determined after PGD(2) was administered. PGD(2) supplementation reduced the incidence and severity of EAU in SJL/J mice in a dose-dependent fashion. The number of T cells in the PGD(2)-treated group was reduced approximately 50% compared with that in mice that were fed a balanced diet. The suppressive effect of PGD(2) on T cell-mediated diseases appears to depend on the suppression of early cytokine production, rather than the differentiation of CD4+ T cells into Th1 or Th2 cells. We conclude that dietary PGD(2) inhibits EAU by suppressing the early cytokine production of effector T cells.Sponsor
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Apple, Nike announce new partnership
Apple and Nike announced a new technology partnership Wednesday. The companies will focus on developing health and fitness applications for the iPhone and iPod touch.
Apple's Steve Jobs didn't disclose a specific timetable for when the new applications will be introduced, but did say they should be available by the end of the year.
From Nike, they said they expect to launch a series of features in the future.
The partnership is a coup for Apple, already the single largest e-commerce retailer in the world. But it also adds a fresh face to its bottom line and reinforces the iPhone's role as a health and fitness device 0b46394aab
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